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Te Mahi Whakaora-Pakeketanga o ia Rā me te Acetyl Dipeptide-1 Cetyl Ester – Whakarei ake i te Rangatahi o te Kiri
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Whakaahuatanga Hua
1.MOA - Tikanga Mahi
Ko te Acetyl Dipeptide-1 Cetyl Ester he peptide biomimetic i hangaia kia rite ki te tikanga maori o te tinana mō te whakaiti i ngā uaua e hua ai ngā raina me ngā kita. He tino whai kiko, he matatau hoki tana tikanga mahi:
Ko te Acetyl Dipeptide-1 Cetyl Ester he peptide biomimetic i hangaia kia rite ki te tikanga maori o te tinana mō te whakaiti i ngā uaua e hua ai ngā raina me ngā kita. He tino whai kiko, he matatau hoki tana tikanga mahi:
Peptide Ārai-Neurotransmitter (Pānga Whakapapa):
*He rite te hanganga matua o te dipeptide ki te pito C-terminal o te pūmua SNAP-25. Ko te SNAP-25 he wāhanga matua o te matatini SNARE, he mea nui mō te tukunga o ngā neurotransmitters (pēnei i te acetylcholine) mai i ngā pito io ki ngā pūtau uaua.
*Mā te whai i tēnei hanganga, ka mahi a Acetyl Dipeptide-1 Cetyl Ester hei aukati whakataetae. Ka whakararuraru i te hanganga o te matatini SNARE, ā, ka whakaiti i te tukunga nui o te acetylcholine i te hononga io-uaua.
*Ka hua ake tēnei i te whakangāwari o ngā uaua iti o te mata, he rite ki te tikanga o ngā paitini io werohanga engari he āhua ā-pā, kāore e pāngia e te pararutiki. Ka "whakangawari" i ngā nekehanga uaua auau e puta ai ngā kita hihiri (hei tauira, ngā waewae o te rākau, ngā rārangi rae, me ngā rārangi kōkō).
HeRōpū cetyl me te Cetyl Ester (Te Whakauru me te Whai Huatanga):
*Ka whakarei ake te rōpū Acetyl i te pumau me te koiora-whakamimicry o te peptide.
*He mea nui te Cetyl Ester (he ester waipiro ngako mekameka roa) mō te wairewatanga o ngā ngako, kia taea ai e te peptide te uru pai ki roto i te stratum corneum me te tae atu ki ōna pae ūnga i roto i ngā paparanga hohonu o te kiri.
2. Ngā Raraunga Whai Hua i roto i te In Vitro
Te Ārai i te Tukunga o ngā Neurotransmitter: Kua whakaatuhia e ngā rangahau in vitro i runga i ngā tauira pūtau neuronal ka taea e Acetyl Dipeptide-1 Cetyl Ester te whakaiti nui i te tukunga o te acetylcholine i runga i te horopeta e whakawhirinaki ana, e whakaū ana i tana tikanga mahi matua.
Te Paitini me te Haumarutanga o te Pūmua: Kua whakaatuhia e te kai te manawanui pai rawa atu i roto i ngā whakamātautau paitini paerewa (hei tauira, i runga i ngā ahurea fibroblast tangata), e tohu ana i tōna haumaru mō te whakamahinga whakapaipai i ngā kukū kua tūtohutia.
Ngā Rangahau Pūmautanga: E whakaatu ana te ngota i te pūmautanga teitei i roto i ngā momo whakatakotoranga whakapaipai (ngā emulsion, ngā serum) i raro i ngā tikanga rokiroki paerewa, e whakarite ana i tōna whai huatanga puta noa i te wā e ora ai te hua.
3. Ngā Hua Hauora
He maha ngā rangahau haumanu, tae atu ki ngā whakamātautau matapo-rua, whakamātautau whakahaere-placebo, kua whakamanahia te whai huatanga o ngā hua kei roto ko te 2-10% Acetyl Dipeptide-1 Cetyl Ester.
Te Whakaiti i te Hōhonutanga me te Rōrahi o ngā Kita:
Akoranga 1: I whakaatuhia i roto i tētahi rangahau 28-rā me tētahi tātai kei roto ko te 5% o te kai he whakahekenga nui i roto i te hohonutanga o ngā kita (tae atu ki te -27%) i te rohe o ngā waewae o te manu, e ai ki ngā tauira kiri me te tātari whakaahua.
Akoranga 2I whakaatuhia e tētahi rangahau 56-rā te whakapainga tonu, me te whakahekenga o te rahinga o ngā kita i te rohe periocular neke atu i te 30%.
Te Whakaiti i te Kaha o te Werowero (Kaute Hauora):
I whakaūtia e te aromatawai haumanu a te tākuta kiri te hekenga kitea o te kaha o ngā raina āhua i te rae me te glabella (i waenganui i ngā tukemata). I aromatawaitia ngā kaiuru he "maeneene" me te "māhorahora" te kiri.
Ultrasound Taumira-Teitei:
Kua whakaatuhia e te whakaahua ultrasound o te kiri he hekenga ine o te kaha o te whakakiki o ngā uaua o raro, e whakaatu ana i te taunakitanga tūturu o tōna mahi "rite ki te Botox".
Kōtaha Haumaru
He tino pai te āhua haumaru o te Acetyl Dipeptide-1 Cetyl Ester. Kāore e whakapataritari, kāore e whakararuraru, ā, e pai ana te manawanui ki tēnei mate, ahakoa he kiri tairongo. Ehara i te rongoā, ā, kāore hoki e pāngia te tinana.
Ngā Huinga Whakakotahi
*Me te Waikawa Hyaluronic me ngā Whakamakuku
*Me ngā Peptides Whakarei i te Korarana/Elastin.
*Me ngā Ārai Matewai
*Me ngā Peptides Whakarei i te Korarana/Elastin.
*Me ngā Ārai Matewai
Ngā Tuhipoka Whakatakotoranga
He pumau i roto i ngā awhe pH e whakamahia ana mō ngā mea whakapaipai (4.0-8.0) ā, ka taea te whakauru ki roto i ngā serum, ngā kirimi, ngā hinu kiri, ngā tiēre kanohi, me ngā kopare kanohi.
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Te Inenga me te Hanganga i Manakohia
Taumata Whakamahinga i Manakohia: 2% ki te 10% i roto i te hua whakamutunga.
*He taumata 2-5% te whai hua mō ngā kereme whānui mō te ārai i ngā kita.
*E taunakitia ana kia 5-10% te taumata mō ngā hua kua tohua, he hua tino pai te mahi e aro ana ki ngā raina whakapūmau hohonu (hei tauira, "ngā mea whakawhāiti i te koroheketanga," "ngā serum whakangāwari i ngā kita").
Ngā Hanganga kua Manakohia:
Ngā Serum me ngā Whakawhānui: He pai mō ngā maimoatanga whai horopeta nui, whai kiko.
Ngā Kirimi me ngā Hinu Kanohi: He tino pai mō te aro atu ki ngā waewae o te rākau.
Ngā Kirimi me ngā Hinu mō te Awatea/Pō: Hei whakangawari i te mata whānui, hei tiaki hoki i te kiri.
Ngā Pāti/Ngā Ārai: Mō te whakamahinga kaha, ā-rohe.
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Botox Pania - He Huarahi Whakakapi
Ko te karere hokohoko matua. He otinga ā-kiri, kāore e pokanoa, hei whakangāwari i ngā raina whakahāngai mā te whai i te tikanga o ngā paitini io werohanga.
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Te Whai Huatanga kua Whakamātauhia e te Hauora
E tautokona ana e ngā raraunga taputapu whaitake me te whakatauranga haumanu, e whakaatu ana i te whakahekenga nui o te hohonutanga me te rahinga o ngā kita i roto i ngā rā 28-56.
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Te Mahi Biomimetic me te Mahi Whaiaro
Mā te hoahoa atamai o te peptide ka taea te aro tika ki te pūtake o ngā kita hihiri me te kore e pararutiki ngā uaua.
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Haumaru me te Manawanui Tino Pai
He pai mō ngā momo kiri katoa, tae atu ki te kiri tairongo, kāore he wā whakaora, kāore hoki he werohanga e hiahiatia ana.
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Te Whānuitanga o te Hanga
He ngāwari te whakauru ki roto i te whānuitanga o ngā hua whakapaipai utu nui, mai i ngā serum ki ngā kirīmi.
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Pūtahitanga Kaha
He tino pai te mahi tahi me ētahi atu hohenga ārai-pakeketanga hei whakarato i tētahi huarahi maha-taha ki te whakaora i te kiri.
Rokiroki
Penapena ki roto i tētahi ipu kua kati i te wāhi maroke i te pāmahana rūma.
Whakamātautau Kararehe
Kāore i whakamatautauria ki ngā kararehe
Huawhenua
Kāore i roto ngā wāhanga i ahu mai i ngā kararehe
GMO
Kāore he raraunga e wātea ana